DISPROPORTION IN PERICYTE/ENDOTHELIAL CELL PROLIFERATION AND MECHANISMS OF INTUSSUSCEPTIVE ANGIOGENESIS PARTICIPATE IN BIZARRE VESSEL FORMATION IN GLIOBLASTOMA

Disproportion in Pericyte/Endothelial Cell Proliferation and Mechanisms of Intussusceptive Angiogenesis Participate in Bizarre Vessel Formation in Glioblastoma

Glioblastoma (GBM) is the most malignant tumor in the brain.In addition to the vascular pattern with thin-walled vessels and findings of sprouting angiogenesis, GBM presents a bizarre microvasculature (BM) formed by vascular clusters, vascular garlands, and glomeruloid bodies.The mechanisms in BM morphogenesis are not well known.Our objective was t

read more

TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia.

Chronic myelomonocytic leukemia (CMML) has recently been associated with a high incidence of diverse mutations in genes such as poise pads in bulk TET2 or EZH2 that are implicated in epigenetic mechanisms.We have performed genome-wide DNA methylation arrays and mutational analysis of TET2, IDH1, IDH2, EZH2 and JAK2 in a group of 24 patients with CM

read more

Effect of Dietary Threonine Addition on Growth Performance, Carcass Characteristics and Serum Parameters in Growing Quails

This research was carried out to determine the effects of diets containing different click here levels of threonine on the performance, carcass characteristics, and serum biochemical parameters of growing Japanese quails.In the study, a total of 240 mixed sex quail chicks at the age of one day were randomly allocated to 6 treatment groups with 4 su

read more